Early this morning, sad news came from the Gu Feng music community: singer Wu En from Luan Feng Ming has passed away. "Signet ring cell carcinoma, the most deceptive type of gastric cancer," subsequently trended on Weibo.
Wu En is a cherished memory of youth for many listeners, with his representative works "Wang Xian," "Tong Dao Shu Tu," and "Ren Jian Zong Wo" widely circulated.
He was diagnosed with gastric signet ring cell carcinoma as early as 2019. Over the next seven years, he continuously fought against the disease, undergoing multiple surgeries and facing the challenges of recurrence and metastasis. In August of this year, he posted that he had entered the terminal stage of the disease, with his condition deteriorating steadily, before sadly passing away.
Gastric signet ring cell carcinoma is the most "deceptive" member of the gastric cancer family. It is a special type, also known as the "King of Gastric Cancers."
Unlike typical gastric cancer, it does not form raised masses but instead infiltrates diffusely within the stomach wall. Under a microscope, the cells are filled with mucus, pushing the nucleus to one side, resembling a signet ring, hence the name.
Gastric signet ring cell carcinoma shows almost no "alarms" in its early stages. Patients often only experience occasional post-meal bloating, loss of appetite, or dull upper abdominal pain, which are nearly identical to symptoms of common gastritis. Under gastroscopy, lesions often appear as only slight congestion or discoloration, making them difficult to identify visually and leading to a high probability of misdiagnosis.
It is highly aggressive and progresses rapidly, with low sensitivity to radiotherapy and chemotherapy. Most patients are diagnosed at an advanced stage, and the 5-year survival rate is significantly lower than that of common gastric adenocarcinoma.
Medical professionals remind people with a family history of gastric disease, Helicobacter pylori infection, or long-term stomach discomfort not to rely solely on symptoms. Regular gastroscopy screenings are essential; do not be misled by its mild "disguise" and miss the optimal window for intervention.